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Microbe-vector Interactions in Vector-borne Diseases

£70.99

Part of Society for General Microbiology Symposia

Editors:
S. H. Gillespie, University College London
G. L. Smith, Imperial College of Science, Technology and Medicine, London
A. Osbourn

B. W. J. Mahy, S. E. Randolph, S. Blanc, S. W. Ding, A. G. Barbour, R. M. Elliott, S. Higgs, S. Weaver, P. S. Mellor, N. A. Ratcliffe, M. M. A. Whitten, S. MacFarlane, D. J. Robinson, M. J. Taylor, J. A. Carlyon, E. Fikrig, B. J. Hinnebusch, P. W. Atkinson, G. A. T. Targett

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Date Published: May 2004
availability: In stock
format: Hardback
isbn: 9780521843126

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Description

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About the Authors

Several billion people are at daily risk of life threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them. It details the elegant biological adaptations that have enabled pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.
- Details the elegant biological adaptations that have enabled pathogens to live with their vectors and in some circumstances control them
- Written by international researchers in the field
- Essential reading for researchers and clinicians working with these diseases
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Reviews & endorsements
'The authors describe the advantages of insects as vectors and their numerous barriers to infection, including physico-chemical barriers, the gut, haemolymph, and the salivary glands themselves.' ASM News

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Product details
- Date Published: May 2004
- format: Hardback
- isbn: 9780521843126
- length: 396 pages
- dimensions: 236 x 158 x 24 mm
- weight: 0.762kg
- contains: 35 b/w illus. 10 colour illus. 14 tables
- availability: In stock
Table of Contents
Preface
1. Vector-borne diseases B. W. J. Mahy
2. Evolution of tick-borne disease systems S. E. Randolph
3. Insect transmission of viruses S. Blanc
4. Interactive silencing of host gene expression S. W. Ding
5. Reducing the prevalence of Borrelia in ticks A. G. Barbour
6. Bunyavirus/mosquito interactions R. M. Elliott
7. How do mosquito vectors live with their viruses? S. Higgs 8. Induction of vector competence S. Weaver
9. Environmental influences on arbovirus infections and vectors P. S. Mellor
10. Vector immunity N. A. Ratcliffe and M. M. A. Whitten
11. Transmission of plant viruses by nematodes S. MacFarlane and D. J. Robinson
12. Wolbachia host-symbiont interactions M. J. Taylor
13. Pathogenic strategies of Anaplasma phagocytophilum, a unique bacterium that colonizes neutrophils J. A. Carlyon and E. Fikrig
14. Interactions of Yersinia pestis with its flea vector that lead to the transmission of plague B. J. Hinnebusch
15. Transgenic malaria P. W. Atkinson
16. Vaccines targeting vectors G. A. T. Targett
Index.
Editors
S. H. Gillespie, University College London
Stephen H. Gillespie is Professor of Medical Microbiology in the Department of Infectious Diseases at University College London, UK.
G. L. Smith, Imperial College of Science, Technology and Medicine, London
Geoffrey L. Smith is a Wellcome Trust Principal Research Fellow and Head of Department of Virology at Imperial College London, UK.
A. Osbourn
Anne Osbourn is a Group leader in the Sainsbury Laboratory, John Innes Centre, Norwich,UK.
Contributors
B. W. J. Mahy, S. E. Randolph, S. Blanc, S. W. Ding, A. G. Barbour, R. M. Elliott, S. Higgs, S. Weaver, P. S. Mellor, N. A. Ratcliffe, M. M. A. Whitten, S. MacFarlane, D. J. Robinson, M. J. Taylor, J. A. Carlyon, E. Fikrig, B. J. Hinnebusch, P. W. Atkinson, G. A. T. Targett