Neurochemistry of Sleep and Wakefulness
- Editors:
- Jaime Monti, Universidad de la República, Uruguay
- S. R. Pandi-Perumal, Mount Sinai School of Medicine, New York
- Christopher M. Sinton, University of Texas Southwestern Medical Center, Dallas
- Date Published: January 2008
- availability: Available
- format: Hardback
- isbn: 9780521864411
Hardback
Other available formats:
eBook
Looking for an inspection copy?
Please email [email protected] to enquire about an inspection copy of this book
-
Pharmacological approaches to our understanding of sleep have been at the forefront of sleep research for many years. Traditional techniques have included the use of pharmacological agonists and antagonists, as well as transmitter-specific lesions. These have been enhanced by the introduction of molecular genetics and the use of transgenes and targeted gene deletion. Neurochemistry of Sleep and Wakefulness is an exceptional, single source of information on the role of the major mammalian neurotransmitter systems involved in the regulation of sleep and waking. With contributions from internationally recognized experts, this book clearly describes how researchers have made use of the myriad techniques in their armamentarium to characterize the role of a given neurotransmitter in the regulation of sleep and waking. Suitable for experimental and clinical pharmacologists, the book will have wider appeal to sleep researchers, psychiatrists and any professional interested in the interdisciplinary areas of neurobiology and pharmacology.
Read more- Describes in detail various CNS neurotransmitter systems, that allows the reader to understand their role in the regulation of sleep and waking
- Shows correlation between a change in the functional activity of a given neurotransmitter with the occurrence of a sleep disorder in Man
- Includes information on the mechanism of action of drugs used for the treatment of sleep disorders
Customer reviews
Not yet reviewed
Be the first to review
Review was not posted due to profanity
×Product details
- Date Published: January 2008
- format: Hardback
- isbn: 9780521864411
- length: 506 pages
- dimensions: 254 x 180 x 28 mm
- weight: 1.172kg
- contains: 54 b/w illus. 8 colour illus.
- availability: Available
Table of Contents
Part I. The Neurochemistry of the States of Sleep and Wakefulness:
1. Neurochemistry of the preoptic hypothalamic hypnogenic mechanism Dennis McGinty, Md. Noor Alam, Hui Gong, Melvi Methippara, Natalia Suntsova, Ruben Guzman-Marin and Ronald Szymusiak
2. Neuroanatomical and neurochemical basis of wakefulness and REM sleep systems Ritchie E. Brown and Robert W. McCarley
3. Rapid eye movement sleep regulation by modulation of the noradrenergic system Birendra N. Mallick, Vibha Madan and Sushil K. Jha
Part II. The Influence of Neurotransmitters on Sleep and Wakefulness:
4. Gamma-aminobutyric acid and the regulation of paradoxical, or rapid eye movement sleep Pierre-Hervé Luppi, Damien Gervasoni, Laure Verret, Romain Goutagny, Christelle Peyron, Denise Salvert, Lucienne Leger and Patrice Fort
5. Acetylcholine modulates sleep and wakefulness: a synaptic perspective Ralph Lydic and Helen A. Baghdoyan
6. Histamine in the control of sleep-wakefulness Mahesh M. Thakkar and Robert W. McCarley
7. Dopamine in behavioral state control David B. Rye and Amanda A. H. Freeman
8. Glutamate neurotransmission and sleep Irwin Feinberg and Ian G. Campbell
9. Serotonin and sleep/wake regulation Jaime M Monti, Héctor Jantos and Daniel Monti
Part III. Changing Perspectives:
10. Melatonin and its receptors: biological function in circadian sleep/wake regulation Daniel P. Cardinali, S. R. Pandi-Perumal and Lennard P. Niles
11. Sleep regulatory factors Levente Kapás and Éva Szentirmai
12. Adenosine and sleep/wake regulation Dag Stenberg and Tarja Porkka-Heiskanen
13. Prostaglandins and the regulation of sleep and wakefulness Osamu Hayaishi and Yoshihiro Urade
14. Neuropeptides and sleep/wake regulation Luis de Lecea
15. Orexins in sleep and wakefulness: rodent models of narcolepsy-cataplexy Christopher M. Sinton and Jon T. Willie
16. The relevance of experimental pharmacology to currently available sleep/wake therapeutics Rafael J. Salin-Pascual.
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email [email protected]
Register Sign in» Proceed
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.
Continue ×Are you sure you want to delete your account?
This cannot be undone.
Thank you for your feedback which will help us improve our service.
If you requested a response, we will make sure to get back to you shortly.
×