Introduction to Cancer Biology
2nd Edition
£44.99
- Author: Robin Hesketh, University of Cambridge
- Date Published: September 2023
- availability: In stock
- format: Paperback
- isbn: 9781009068338
£
44.99
Paperback
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From basic principles to insights into pioneering research, this introductory textbook provides the fundamentals of cancer biology that will enable students of biology and medicine to enter the field with confidence. It opens with a discussion of global cancer patterns, how cancers arise, and the risk factors involved. A description of the normal signalling pathways within cells then explains how DNA mutations affect proteins and what this means for the development and behaviour of tumours. Later chapters discuss methods for tumour detection, biomarker identification and the impact of genome sequencing, before reviewing the development of anti-cancer drugs and exciting current advances in treatment. With 50% new material, including two new chapters on genetic analysis of cancer and cancer chemotherapy, improved pedagogy, examples of revolutionising technologies in drug design and delivery, and useful online resources, this textbook offers an accessible and engaging account of cancer biology for undergraduate and graduate students.
Read more- Provides a step-by-step progression through the basics of cancer, minimising confusion and revealing the wonder of the molecular biology of cancer
- Describes basic features of normal cell signalling before integrating key mutations into the picture, making it easy for students to grasp the range of strategies that tumour cells can use to neutralise drugs
- Covers the latest development in genetic analysis of cancer and chemotherapy, allowing students to gently grasp the range of anti-cancer drugs in clinical use
- Describes the range of approaches now under development in the design of drugs and their delivery along with relevant illustrations and examples to summarise how effective they have been and their potential for further development
- Includes assessment material, ranging from 'Pause and Recap' boxes, end-of-chapter questions, and an online test bank
- Designed for students of biology and natural sciences as well as medical students and qualified doctors who are challenged t
Reviews & endorsements
'A comprehensive, engagingly written, accurate overview of a topic that has continued to rapidly evolve in recent years. As our knowledge of cancer's molecular underpinnings advances, it is essential to remain up-to-date and this book delivers. Each chapter is full of concise explanations and wonderful illustrations that convey complex concepts in a straightforward way. I highly recommend this valuable resource to all students of biology and medicine.' Andrew Lam, M.D., University of Massachusetts Medical School
See more reviews'The new edition of Introduction to Cancer Biology has been well worth waiting for. It develops logically from the previous edition and brings our current understanding of all aspects of the nature of cancer biology up to date. Central to the book are chapters dealing with DNA, oncogenes, tumour suppressor genes and signalling pathways. The chapters convey the historical development of these ideas into our current understanding. Thus, the book is suitable for students, undergraduates and postgraduates with an interest or need, to develop an overview of cancer research.' Tony Bradshaw, Oxford Brookes University
'This textbook has easy to understand figures and clearly laid out chapters. My favourite is the logical roadmap describing how one should teach using this textbook. I never saw that before. I think the students will appreciate the 'pause and recap' throughout the book; what a great way to check your knowledge one step at a time.' Luiza Nogaj, Mount Saint Mary's University Los Angeles
'A comprehensive look at cancer biology and treatment with chemical-level precision.' John Schmidt, Villanova University, Pennsylvania
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×Product details
- Edition: 2nd Edition
- Date Published: September 2023
- format: Paperback
- isbn: 9781009068338
- length: 450 pages
- dimensions: 264 x 203 x 22 mm
- weight: 1.11kg
- availability: In stock
Table of Contents
Preface
1. Lessons from epidemiology
2. Causes of cancer
3. Genetic analysis of cancer
4. Signaling in normal cells
5. 'Cancer genes': Mutations and cancer development
6. What is a tumour? 7. Cancer signaling networks
8. Cancer detection, diagnosis and radiotherapy
9. Cancer chemotherapy
10. The future of cancer detection and treatment
Appendix A: Tumour grading and staging
Appendix B: Classes of major oncoproteins
Appendix C: Major tumour suppressor genes
Appendix D: Ten major cancers at a glance
Glossary, References, Index.
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