Statistical Evaluation of Mutagenicity Test Data
£60.99
- Editor: David J. Kirkland
- Date Published: January 2008
- availability: Available
- format: Paperback
- isbn: 9780521048149
£
60.99
Paperback
Other available formats:
Hardback
Looking for an inspection copy?
This title is not currently available on inspection
-
This rigorous and practical account of the interpretation of mutagenicity test data draws upon the expertise of toxicologists and statisticians. Chemicals, such as drugs, food additives and pesticides, all need careful screening to eliminate potentially mutagenic compounds. Although guidelines exist on the performance of these tests, advice on data evaluation is scarce; this volume provides the statistical background necessary for toxicologists to understand, design and interpret mutagenicity tests. In addition to the nine chapters dealing with the different tests employed, there is an introductory chapter on some of the statistical principles involved, a glossary of useful terms and an appendix providing vital information on the availability of computer software. A large team of contributors and editors working under the auspices of the United Kingdom Environmental Mutagen Society (UKEMS) have contributed a wealth of first-hand experience in compiling this immensely practical book of use to both research and industrial toxicologists.
Customer reviews
Not yet reviewed
Be the first to review
Review was not posted due to profanity
×Product details
- Date Published: January 2008
- format: Paperback
- isbn: 9780521048149
- length: 312 pages
- dimensions: 229 x 153 x 20 mm
- weight: 0.479kg
- contains: 39 b/w illus.
- availability: Available
Table of Contents
Steering group
Contributors
Preface
List of abbreviations
1. Statistics and genetic toxicology - setting the scene D. P. Lovell
2. Analysis of data from microbial colony assays G. A. T. Mahon, M. H. L. Green, B. Middleton, I. de G. Mitchell, W. D. Robinson and D. J. Tweats (group leader)
3. Mammalian cell gene mutation assays based upon colony formation C. F. Arlett (group leader), D. M. Smith, G. M. Clarke, M. H. L. Green, J. Cole, D. B. McGregor and J. C. Asquith
4. Statistical evaluation of bacterial/mammalian fluctuation tests W. D. Robinson, M. H. L. Green (group leader), J. Cole, M. J. R. Healy, R. C. Garner and D. Gatehouse
5. Analysis of data from in vitro cytogenetic assays C. Richardson (group leader), D. A. Williams, J. A. Allen, G. Amphlett, D. O. Chanter and B. Phillips
6. Statistical methods for sister chromatid exchange experiments D. Cooke, J. Allen, M. G. Clare, C. J. Doré and L. Henderson (group leader)
7. Statistical analysis of in vivo cytogenetic assays D. P. Lovell, D. Anderson (group leader), R. Albanese, G. E. Amphlett, G. Clare, R. Ferguson, M. Richold, D. G. Papworth and J. R. K. Savage
8. Statistical methods for the dominant lethal assay D. O. Chanter, D. Anderson, A. Bateman, D. P. Lovell, A. K. Palmer, M. T. Stevens and M. Richold (group leader)
9. Statistical methods for the design and analysis of mutation experiments with the fruit fly Drosophila melanogaster R. D. Combes (group leader), J. Bootman, M. G. Ford, J. Hepworth and D. W. Salt
Appendices
Index.
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email [email protected]
Register Sign in» Proceed
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.
Continue ×Are you sure you want to delete your account?
This cannot be undone.
Thank you for your feedback which will help us improve our service.
If you requested a response, we will make sure to get back to you shortly.
×