Monoclonal Antibodies
$122.00 (M)
Part of Postgraduate Medical Science
- Editors:
- Mary A. Ritter, Royal Postgraduate Medical School, London
- Heather M. Ladyman, Royal Postgraduate Medical School, London
- Date Published: February 1995
- availability: Available
- format: Paperback
- isbn: 9780521425032
$
122.00
(M)
Paperback
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This book is among the first to combine technical and clinical aspects of the subject. It aims to provide a unique combination of the production (by both cellular and molecular biology techniques), structure and functional characteristics of monoclonal antibodies, together with detailed discussions of the various analytic, diagnostic and therapeutic applications of these antibodies. Many areas of clinical medicine benefit from this type of study including histopathology, oncology, transplantation, infectious diseases, rheumatology, haematology, and dermatology.
Read more- Provides a unique combination of practical/technical aspects of monoclonal antibodies with their clinical applications
- Based on the highly successful Royal Postgraduate Medical School courses on monoclonal antibodies
- From production of monoclonal antibodies all the way through to therapeutic applications
Reviews & endorsements
"It is a pleasure to recommend this balanced, cogent book to all pathologists. Each chapter retains the focus of the editors, and they are coherent and congruent. The book will help the busy pathologist interact in a more perceptive manner with clinical colleagues who want these procedures performed...this book is must reading and a fantastic bargain." Bernard M. Wagner, Modern Pathology
See more reviews"This book is highly recommended." John A. Robinson, M.D., Doddy's Health Sciences Book Review Journal
"...This clear and concise review gives a detailed analysis of the emerging science of monoclonal antibodies. The user-friendly information is presented in diagrams and charts that simplify and supplement the text...unique, because it effectively focuses on both basic and clinical aspects. It can be read by both researchers and clinicians. The style of the text flows well for easy reading. The text is well-referenced...I would recommend this book to anyone interested in this area of medicine." Gordon Sussman, Annals CRMCC
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×Product details
- Date Published: February 1995
- format: Paperback
- isbn: 9780521425032
- length: 500 pages
- dimensions: 245 x 170 x 25 mm
- weight: 0.798kg
- contains: 55 b/w illus. 38 tables
- availability: Available
Table of Contents
1. Introduction
2. Production of monoclonal antibodies
3. Antigen–antibody interactions: how affinity and kinetics affect assay design and selection procedures
4. The production and characterisation of synthetic peptide-derived antibodies
5. Human monoclonal antibodies
6. Bispecific monoclonal antibodies
7. The production of antibodies using phage display libraries
8. Genetic manipulation of monoclonal antibodies
9. Monoclonal antibodies in diagnostic immunoassays
10A. Monoclonal antibodies in diagnostic pathology
10B. In vivo targeting of monoclonal antibodies for immunoscintigraphy and therapy of human malignancies
11A. Monoclonal antibodies in infectious disease: diagnosis
11B. Monoclonal antibodies in the prophyllaxis and therapy of infectious disease
12A. Monoclonal antibodies in transplantation: immunohistology
12B. Monoclonal antibodies in transplantation: experimental studies on in vivo immunosuppression
12C. Monoclonal antibodies in transplantation: prophyllaxis of graft-versus-host disease after bone marrow transplantation
12D. Monoclonal antibodies in transplantation: use as therapeutic agents in clinical organ transplantation
13. Monoclonal antibodies and the skin
14. Monoclonal antibodies in endocrinology
15. Monoclonal antibodies in rheumatology
16. Technical appendix.
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