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Liver Disease in Children

5th Edition

£201.00

Matthew Gillen, Stacey Huppert, Frederick Suchy, Saul Karpen, James Squires, Estella Alonso, Evelyn Hsu, Karen Murray, Benjamin Shneider, Vicky Lee Ng, Amy Feldman, Ronald Sokol,Philip Rosenthal, Leina Alrabadi, Jorge Bezerra, Akihiro Asai, Greg Tiao, Bhargava Mullapudi, William Balistreri, Katherine Satrom, Glenn R. Gourley, Frederick J. Suchy, Shikha Sundaram,Binita Kamath, Nancy Spinner, David Piccoli, Jason Soden, James Heubi, Frank DiPaola, S. Kathryn Smith, Hong-Yuan Hsu, Mei-Hwei Chang, Jim Squires, Nanda Kerkar, Cara L. Mack, Simon Lam, Eve Roberts, Nedim Hadžić, Shawn McCandless, David Rudnick, David Perlmutter, Lauren Lazar, Meghana Sathe, Drew Feranchak, Peter Witters, Eva Morava, Fayez Ghishan, Sarah Taylor, Michael R. Narkewicz, Robert Desnick, Manisha Balwani, Karl Anderson, Grant Mitchell, Fernando Alvarez, Pramod Mistry, Beth Thurberg, Gregory Grabowski, Kenneth Setchell, Jerry Vockley, Austin Larson, Rohit Kohli, Kevin Bove, Stavra Xanthakos, Paul Watkins, Lingxiao Chen, Nancy Braverman, Kimberly A. Kripps, Derek A. Wong, Donald Novak, Kathleen Campbell, Ronen Arnon, Jaime Chu, Milton Finegold, Nedim Hadzic, Soo-Jin Cho, Kyle Jensen, Marianne Kavan, Manuel Rodriguez-Davalos, Rick Superina
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  • Date Published: March 2021
  • availability: In stock
  • format: Hardback
  • isbn: 9781108843515

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  • Liver disease in children is increasing in prevalence, placing a huge burden on healthcare systems and often requiring long-term management. Offering an integrative approach to the science and clinical practice of pediatric hepatology, this is the definitive reference text for improved diagnosis and treatment strategies. In the new edition of this authoritative text, chapters have been thoroughly revised in line with major advances in the field, such as recognizing the increased frequency of fatty liver disease, and how genetic testing has the potential to establish earlier diagnoses for a variety of diseases. Disorders covered include cholestasis, metabolic disorders and hepatitis, with their presentation across the spectrum of infancy, childhood and adolescence discussed. The indications and surgical aspects of liver transplant are explained and post-transplant care is described in detail. This is a valuable resource for pediatricians, hepatologists, gastroenterologists and all clinicians involved in the care of children with liver diseases.

    • Fully updated to reflect advances in genomics, molecular medicine and personalized therapy, allowing readers to apply this knowledge for improved early diagnoses and treatment
    • Comprehensively covers every aspect of pediatric liver disease including current approaches to diagnosis and treatment, across the spectrum of infancy, childhood and adolescence
    • Three new Associate Editors and several new contributors add a fresh perspective and provide additional expertise to the book, complementing the experience of the established authors
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    Product details

    • Edition: 5th Edition
    • Date Published: March 2021
    • format: Hardback
    • isbn: 9781108843515
    • length: 870 pages
    • dimensions: 286 x 223 x 42 mm
    • weight: 2.65kg
    • contains: 163 b/w illus. 135 colour illus.
    • availability: In stock
  • Table of Contents

    Section 1. Pathophysiology of Pediatric Liver Disease:
    1. Liver development
    2. Functional development of the liver
    3. Mechanisms of bile formation and the pathogenesis of cholestasis
    4. Acute liver failure in children
    5. Cirrhosis and chronic liver failure in children
    6. Portal Hypertension in children
    7. Laboratory assessment of liver function and injury in children
    Section 2. Cholestatic Liver Disease:
    8. Approach to the infant with cholestasis
    9. Medical and nutritional management of cholestasis in infants and children
    10. Neonatal hepatitis and congenital infections
    11. Biliary atresia and other disorders of the extrahepatic bile ducts
    12. Neonatal jaundice and disorders of bilirubin metabolism
    13. Familial hepatocellular cholestasis
    14. Alagille Syndrome
    15. Intestinal failure associated liver disease
    16. Diseases of the gallbladder in infancy, childhood, and adolescence
    Section 3. Hepatitis and Immune Disorders:
    17. Hepatitis A and hepatitis E virus in children
    18. Hepatitis B virus infection in children
    19. Hepatitis C virus infection in children
    20. Autoimmune hepatitis in children
    21. Sclerosing cholangitis in children
    22. Drug-induced liver disease in children
    23. Liver disease in immunodeficiencies in children
    Section 4. Metabolic Liver Disease:
    24. Laboratory diagnosis of inborn errors of liver metabolism
    25. α1-Antitrypsin Deficiency
    26. Cystic fibrosis liver disease in children
    27. Inborn errors of carbohydrate metabolism
    28. Copper metabolism and copper storage disorders in children
    29. Iron storage disorders in children
    30. Heme biosynthesis and the porphyrias in children
    31. Tyrosinemia in children
    32. Lysosomal storage disorders in children
    33. Disorders of bile acid synthesis and metabolism in children
    34. Inborn errors of fatty acid oxidation
    35. Mitochondrial hepatopathies
    36. Non-alcoholic fatty liver disease in children
    37. Peroxisomal disorders in children
    38. Urea cycle disorders in children
    Section 5. Other Considerations and Issues in Pediatric Hepatology:
    39. Bacterial, parasitic, and fungal infections of the liver in children
    40. Systemic disease and the liver in children
    41. Fibrocystic liver disease in children
    42. Tumors of the liver in children
    43. Liver transplantation in children: indications and surgical aspects
    44. Liver transplantation in children: post-transplant care.

  • Editors

    Frederick J. Suchy, University of Colorado, Children’s Hospital Colorado, Aurora
    Frederick J. Suchy MD is Professor of Pediatrics, Chief Research Officer, Digestive Health Institute, Section of Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, and University of Colorado School of Medicine, Aurora, CO, USA.

    Ronald J. Sokol, University of Colorado, Children’s Hospital Colorado, Aurora
    Ronald J. Sokol MD is Arnold Silverman MD Endowed Chair in Digestive Health, Chief, Section of Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, and University of Colorado School of Medicine, Aurora, CO, USA.

    William F. Balistreri, Cincinnati Children’s Hospital Medical Center, Cincinnati
    William F. Balistreri MD is Dorothy M. M. Kersten Professor of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital, Cincinnati, OH, USA.

    Associate Editor

    Jorge A. Bezerra, Cincinnati Children’s Hospital Medical Center, Cincinnati
    Jorge A Bezerra, MD is the William and Rebecca Balistreri Chair in Pediatric Hepatology, Professor of Pediatrics, and Director, Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH, USA.

    Cara L. Mack, University of Colorado, Children’s Hospital Colorado, Aurora
    Cara L. Mack, MD is Professor of Pediatrics, Hewit/Andrews Chair in Pediatric Liver Disease, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, and University of Colorado School of Medicine, Aurora, CO, USA.

    Benjamin L. Shneider, Texas Children’s Hospital, Houston
    Benjamin L. Shneider MD is George Peterkin Endowed Chair, Service Chief, Pediatric Gastroenterology, Hepatology and Nutrition, Texas Children's Hospital, and Section Head, Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, TX, USA.

    Contributors

    Matthew Gillen, Stacey Huppert, Frederick Suchy, Saul Karpen, James Squires, Estella Alonso, Evelyn Hsu, Karen Murray, Benjamin Shneider, Vicky Lee Ng, Amy Feldman, Ronald Sokol,Philip Rosenthal, Leina Alrabadi, Jorge Bezerra, Akihiro Asai, Greg Tiao, Bhargava Mullapudi, William Balistreri, Katherine Satrom, Glenn R. Gourley, Frederick J. Suchy, Shikha Sundaram,Binita Kamath, Nancy Spinner, David Piccoli, Jason Soden, James Heubi, Frank DiPaola, S. Kathryn Smith, Hong-Yuan Hsu, Mei-Hwei Chang, Jim Squires, Nanda Kerkar, Cara L. Mack, Simon Lam, Eve Roberts, Nedim Hadžić, Shawn McCandless, David Rudnick, David Perlmutter, Lauren Lazar, Meghana Sathe, Drew Feranchak, Peter Witters, Eva Morava, Fayez Ghishan, Sarah Taylor, Michael R. Narkewicz, Robert Desnick, Manisha Balwani, Karl Anderson, Grant Mitchell, Fernando Alvarez, Pramod Mistry, Beth Thurberg, Gregory Grabowski, Kenneth Setchell, Jerry Vockley, Austin Larson, Rohit Kohli, Kevin Bove, Stavra Xanthakos, Paul Watkins, Lingxiao Chen, Nancy Braverman, Kimberly A. Kripps, Derek A. Wong, Donald Novak, Kathleen Campbell, Ronen Arnon, Jaime Chu, Milton Finegold, Nedim Hadzic, Soo-Jin Cho, Kyle Jensen, Marianne Kavan, Manuel Rodriguez-Davalos, Rick Superina

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