Monoclonal Antibodies
Part of Postgraduate Medical Science
- Editors:
- Mary A. Ritter, Royal Postgraduate Medical School, London
- Heather M. Ladyman, Royal Postgraduate Medical School, London
- Date Published: January 1995
- availability: Available
- format: Paperback
- isbn: 9780521425032
Paperback
Looking for an inspection copy?
This title is not currently available on inspection
-
Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject. Monoclonal antibodies provide highly specific reagents with which to identify, analyse, quantitate and manipulate molecules - both in solution and in solid phase, such as at a cell surface. The aim of this book is therefore to provide a unique combination of the production (by both cellular and molecular biology techniques), structure and functional characteristics of monoclonal antibodies, together with detailed discussions of the various analytic, diagnostic and therapeutic applications of these antibodies in many areas of clinical medicine, including histopathology, oncology, transplantation, infectious diseases, rheumatology, haematology and dermatology.
Read more- Provides a unique combination of practical/technical aspects of monoclonal antibodies with their clinical applications
- Based on the highly successful Royal Postgraduate Medical School courses on monoclonal antibodies
- From production of monoclonal antibodies all the way through to therapeutic applications
Reviews & endorsements
'This book provides a timely overview of the production and application of mAbs … if everyone using mAbs in their research were to read this then the work of referees might be much reduced … a valuable resource to anyone working with, or contemplating working with, mAbs.' Alan Trudgett, Society for General Microbiology Quarterly
See more reviews'… provides a comprehensive account of the different techniques available for the generation of mabs.' Molecular Medicine Today
'The editors have done a fine job. There is little redundancy between chapters, the text is clear and all the contributions are well referenced.' British Toxicology Society Newsletter
Customer reviews
Not yet reviewed
Be the first to review
Review was not posted due to profanity
×Product details
- Date Published: January 1995
- format: Paperback
- isbn: 9780521425032
- length: 500 pages
- dimensions: 245 x 170 x 25 mm
- weight: 0.798kg
- contains: 55 b/w illus. 38 tables
- availability: Available
Table of Contents
1. Introduction
2. Production of monoclonal antibodies
3. Antigen–antibody interactions: how affinity and kinetics affect assay design and selection procedures
4. The production and characterisation of synthetic peptide-derived antibodies
5. Human monoclonal antibodies
6. Bispecific monoclonal antibodies
7. The production of antibodies using phage display libraries
8. Genetic manipulation of monoclonal antibodies
9. Monoclonal antibodies in diagnostic immunoassays
10A. Monoclonal antibodies in diagnostic pathology
10B. In vivo targeting of monoclonal antibodies for immunoscintigraphy and therapy of human malignancies
11A. Monoclonal antibodies in infectious disease: diagnosis
11B. Monoclonal antibodies in the prophyllaxis and therapy of infectious disease
12A. Monoclonal antibodies in transplantation: immunohistology
12B. Monoclonal antibodies in transplantation: experimental studies on in vivo immunosuppression
12C. Monoclonal antibodies in transplantation: prophyllaxis of graft-versus-host disease after bone marrow transplantation
12D. Monoclonal antibodies in transplantation: use as therapeutic agents in clinical organ transplantation
13. Monoclonal antibodies and the skin
14. Monoclonal antibodies in endocrinology
15. Monoclonal antibodies in rheumatology
16. Technical appendix.
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email [email protected]
Register Sign in» Proceed
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.
Continue ×Are you sure you want to delete your account?
This cannot be undone.
Thank you for your feedback which will help us improve our service.
If you requested a response, we will make sure to get back to you shortly.
×