Endothelial Biomedicine
$394.00 ( ) USD
- Editor: William C. Aird, Harvard University, Massachusetts
- Date Published: October 2007
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
- format: Adobe eBook Reader
- isbn: 9780511332166
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The endothelium, the cell layer that forms the inner lining of blood vessels, is a spatially distributed system that extends to all reaches of the human body. Today, clinical and basic research demonstrates that the endothelium plays a crucial role in mediating homeostasis and is involved in virtually every disease, either as a primary determinant of pathophysiology or as a victim of collateral damage. Indeed, the endothelium has remarkable, though largely untapped, diagnostic and therapeutic potential. This volume endeavors to bridge the bench-to-bedside gap in endothelial biomedicine, with the goal of advancing research and development and improving human health. The book is the first to systematically integrate knowledge about the endothelium from different organ-specific disciplines, including neurology, pulmonary, cardiology, gastroenterology, rheumatology, infectious disease, hematology-oncology, nephrology, and dermatology. Moreover, it is unique in its interdisciplinary approach, drawing on expertise from such diverse fields as evolutionary biology, comparative biology, molecular and cell biology, mathematical modeling and complexity theory, translational research, and clinical medicine.
Read more- Employs multidisciplinary and interdisciplinary approaches to promote the endothelium as a clinically relevant organ
- A single definitive about the endothelium at the level of the single cell, the blood vessel and the whole organism
- Provides new insights into the endothelium as an organizing principle in health and disease
Reviews & endorsements
"Dr William Aird reveals to us the landscape of this new field in his masterpiece...This comprehensive and authoritative tome is the work of many contributors, but the hand of the editor is seen in every chapter...This is an entertaining, thought-provoking, and exhaustive scholarly work. It must be read by those who aspire to become vascular biologists, and it is a useful reference for those in related fields."
Circulation, the Journal of the American Heart AssociationSee more reviews"Endothelial Biomedicine is an intellectual tour de force that is a useful reference, comprehensive textbook, and thoroughly engaging work."
Journal of the American Medical Association"This volume is surely the most comprehensive account of the vascular endothelium ever compiled and, as such is somewhat daunting at first inspection. However, consisting of five parts and compromising of nearly 200 separate essays, it is a tour de force and represents a very significant achievement and an invaluable resource."
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×Product details
- Date Published: October 2007
- format: Adobe eBook Reader
- isbn: 9780511332166
- contains: 81 tables
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
Table of Contents
Part I. Context
Part II. Endothelial Cell as Input-Output Device
Part III. Vascular Bed/Organ Structure and Function in Health and Disease
Part IV. Diagnosis and Treatment
Part V. Challenges and Opportunities.
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