Genes and Aging
- Author: M. S. Kanungo, Banaras Hindu University, Varanasi, India
- Date Published: September 2005
- availability: Available
- format: Paperback
- isbn: 9780521019941
Paperback
Other available formats:
eBook
Looking for an inspection copy?
This title is not currently available for inspection. However, if you are interested in the title for your course we can consider offering an inspection copy. To register your interest please contact [email protected] providing details of the course you are teaching.
-
The maximum life span of multicellular organisms varies greatly: for a fruitfly it is about 30 days, for a dog about 20 years, and for a human about 100 years. Despite these differences, all animals show a similar pattern of their life spans - growth, adulthood, and aging, followed by death. The basic cause of aging in multicellular organisms (eukaryotes) lies at the level of the genes, although nutrition and various types of stresses do influence the rate and pattern of aging. This book reviews the molecular biology of the gene in relation to aging. Until about a decade ago it was not possible to probe into the types of changes that occur in eukaryotic genes, due to their enormous complexity. The use of genetic engineering techniques, however, is beginning to unravel the changes that occur in the genes as an organism ages: such as the changing expression of specific genes under normal conditions and under various types of stress, the changes in the regulatory roles of the sequences in the promotor regions of genes, conformational changes that may occur in genes during aging, and the protein factors that are involved in the aging process. The author presents basic information on eukaryotic genes and follows this with details of the changes that occur in their structure and function during aging. He reviews the latest studies being carried out in various laboratories, outlines the gaps and deficiencies in our present knowledge and suggests the most profitable future areas of research. Genes and Aging is for all students and researchers interested in the molecular biology of aging.
Customer reviews
Not yet reviewed
Be the first to review
Review was not posted due to profanity
×Product details
- Date Published: September 2005
- format: Paperback
- isbn: 9780521019941
- length: 340 pages
- dimensions: 234 x 155 x 19 mm
- weight: 0.487kg
- contains: 60 b/w illus. 12 tables
- availability: Available
Table of Contents
1. Introduction
2. Phenotypic changes during ageing
3. Chromatin
4. Eukaryotic genes
5. Changes in gene expression during aging
6. Theories of aging
7. Conclusions and future prospects
References
Index.
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email [email protected]
Register Sign in» Proceed
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.
Continue ×Are you sure you want to delete your account?
This cannot be undone.
Thank you for your feedback which will help us improve our service.
If you requested a response, we will make sure to get back to you shortly.
×