Pharmacogenetics of Psychotropic Drugs
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- Editor: Bernard Lerer, Hadassah-Hebrew Medical Center, Jerusalem
- Date Published: January 2005
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
- format: Adobe eBook Reader
- isbn: 9780511007453
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This book provides a conceptual framework for understanding and studying the pharmacogenetics of psychotropic drugs, reviews advances in the field, and describes the findings that have already emerged. Coverage extends to antipsychotics, antidepressants and mood stabilizing, cognitive-enhancing and anxiolytic drugs. The volume also examines the interface of pharmacogenetics with substance dependence and brain imaging, and considers its impact on the biotechnology and pharmaceutical industries. This book defines the young field of pharmacogenetics as it applies to psychotropic drugs, and is therefore an essential reference for all clinicians and researchers involved.
Read more- Was the first book to survey the new field of pharmacogenetics as applied to psychotropics
- Editor and contributors at the forefront of the field
- Covers all the main classes of psychotropic drugs, with implications for drug development and clinical practice
Reviews & endorsements
"This book gives a comprehensive review of the current state of the art covering almost all aspects of psychiatric pharmacogenetics. It provides an excellent introduction to the newcomer in this field and at the same time it is a most valuable source of information also for the experts." JÜrgen Brockmöller, Georg-August-University, Acta Psychiatrica Scandinavica
See more reviews"Overall, this is a well-written book on a subject which is often found complicated and difficult." European Journal of Clinical Pharmacology
"The book does an excellent job of providing a comprehensive overview of the field of psychopharmacogenetics and reviewing pertinent research findings.... As a whole, Pharmacogenetics of Psychotropic Drugs is an exceptional text.... Anyone who works with psychotropic drugs should have a copy of this text." The Annals of Pharmacotherapy
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×Product details
- Date Published: January 2005
- format: Adobe eBook Reader
- isbn: 9780511007453
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
Table of Contents
Part I. Introduction:
1. Genes and psychopharmacology: exploring the interface Bernard Lerer
Part II. Clinical Background and Research Design:
2. From pharmacogenetics to pharmacogenomics of psychotropic drug response Anil K. Malhotra
3. Neuropsychopharmacology: the interface between genes and psychiatric nosology Thomas A. Ban
4. Methodological issues in psychopharmacogenetics Sheldon H. Preskorn
5. Statistical approaches in psychopharmacogenetics Fabio Macciardi
Part III. Molecular Background:
6. The psychopharmacogenetic-neurodevelopmental interface in serotonergic gene pathways K. Peter Lesch, Jens Benninghoff and Angelika Schmitt
7. RNA processing regulation and interindividual variation Colleen M. Niswender and Linda K. Hutchinson
Part IV. Pharmacokinetics:
8. Pharmacogenetics of psychotropic drug metabolism Vural Ozdemir, Angela D. M. Kashuba, Vincenzo S. Basile and James L . Kennedy
9. Pharmacogenetics of chiral psychotropic drugs Pierre Baumann and Chin B. Eap
Part V. Specific Psychotropic Drugs and Disorders:
10. Clozapine response and genetic variation in neurotransmitter receptor targets David A. Collier, Maria J. Arranz, Sarah Osborne, Katherine J. Aitchison, Janet Munro, Dalu Mancama and Robert W. Kerwin
11. Genetic factors underlying drug-induced tardive dyskinesia Ronnen H. Segman and Bernard Lerer
12. Functional gene-linked polymorphic regions in pharmacogenetics Marco Catalano
13. Alternative phenotypes and the pharmacogenetics of mood and anxiety disorders Emanuela Mundo and James L. Kennedy
14. Pharmacogenetics of anxiolytic drugs and the GABA-benzodiazepine receptor complex Smita A. Pandit, Spilios V. Argyropoulous, Patrick G. Kehoe and David J. Nutt
15. Genetic factors and long-term prophylaxis in bipolar disorder Martin Alda
16. Genetic influences on responsiveness to anticonvulsant drugs Thomas N. Ferraro
17. Apolipoprotein E as a marker in the treatment of Alzheimer's disease Keith Schappert, Pierre Sevigny and Judes Poirier
18. Genetic variation and drug dependence risk factors Joel Gelernter and Henry Kranzler
Part VI. Pharmacogenetics and Brain Imaging:
19. Brain imaging and pharmacogenetics in Alzheimer's disease and schizophrenia Steven G. Potkin, James L. Kennedy and Vincenzo S. Basile
Part VII. Industry perspectives:
20. Pharmacogenetics in psychotropic drug discovery and development William Z. Potter, AnnCatherine Van Lone and Larry Altstiel
21. High-throughput single nucleotide polymorphism genotyping Anne Shalom and Ariel Darvasi
Index.-
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