Screening for Down's Syndrome
Out of Print
- Editors:
- J. G. Grudzinskas, Royal London Hospital
- T. Chard, St Bartholomew's Hospital, London
- M. Chapman, United Medical and Dental Schools, Guy's Campus, London
- H. Cuckle
- Date Published: November 1994
- availability: Unavailable - out of print August 2004
- format: Hardback
- isbn: 9780521452717
Out of Print
Hardback
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This important new publication summarises the recent exciting advances in screening for Down's syndrome. It addresses important clinical questions such as: risk assessment, who to screen, when to screen, which techniques to use, and the organisation of screening programmes nationally and internationally. An international and authoritative team of authors has been invited to assess the latest developments in this rapidly advancing area. The volume provides a critical and much needed evaluation of the potential and limitations of new and established techniques for screening for Down's syndrome. It will serve as an essential source of information for all those involved in pre-natal diagnosis and the provision of obstetric care.
Read more- This is the first volume to focus exclusively on screening for Down's syndrome
- Fully up to date in an area which has significant recent advances
- This topic is attracting widespread interest in the medical community
Reviews & endorsements
'This text marks a milestone in the screening for Down's syndrome. It presents an up-to-date and in-depth view of the current situation and undoubtedly will become a point of reference for all clinical staff involved in this important area of screening.' British Journal of Biomedical Science
See more reviews'Screening for Down's Syndrome is a well presented book, ideal for those practising in the developing field of prenatal diagnosis.' Modern Midwife
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×Product details
- Date Published: November 1994
- format: Hardback
- isbn: 9780521452717
- length: 358 pages
- dimensions: 235 x 156 x 22 mm
- weight: 0.716kg
- contains: 77 b/w illus. 67 tables
- availability: Unavailable - out of print August 2004
Table of Contents
1. Down's Syndrome (DS) epidemiology and biochemical screening
2. Perception of risk
3. Risk estimation in DS screening policy and practice
4. Screening test combination: a statistical overview
5. Measurement of human chorionic gonadotrophin (hCG) as a screening test for DS
6. The measurement of hCG subunits in screening for DS
7. The measurement of free beta hCG in screening for DS
8. Multiple hCG-related molecules
9. Is the measurement of unconjugated oestriol of value in screening for DS?
10. Inhibin and CA125 in DS screening
11. SPI in DS screening
12. Ultrasound and DS
13. Prenatal diagnosis using fetal cells isolated from maternal blood
14. Rapid detection of chromosome aneuploidies in uncultured fetal cells using fluorescence in situ hybridization
15. Organisation of screening programmes - a British experience
16. The California experience
17. The Dutch experience
18. French experience
19. The United Kingdom national external quality assessment scheme for screening for DS
20. Training obstetricians and midwives to offer serum screening for DS
21. Biochemical screening for DS in the first trimester
22. Screening for DS
23. Mid-trimester biochemistry in prediction of 3rd trimester complications.
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