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Sex Determination, Differentiation and Intersexuality in Placental Mammals

Author: R. H. F. Hunter, University of Montreal and University of Edinburgh

Date Published: April 2011
availability: Available
format: Paperback
isbn: 9780521182294

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About the Authors

The subject of this fascinating book is how and why males become male and females become female and what factors may lead to intersexuality. Coming from a molecular biology perspective, Professor Hunter uses examples of intersexuality, chimeras, and asymmetries to describe the underlying molecular basis of sexual differentiation and determination. He explains how genetic instruction can prompt myriad developmental problems. Reproductive physiologists and geneticists from agriculture to veterinary medicine will find this a stimulating topic.
- Examples from a wide range of mammals
- Examines molecular basis of sex and its abnormalities
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Reviews & endorsements
"...provides a clear and factual account of the experimental evidence that has led to the present position, against a background of normal and abnormal sexual development....very readable....Hunter sets out the relevant facts and hypotheses in a perfectly detached manner, allowing readers to make up their own minds. The book is eminently suitable for the advanced students for whom it is intended, and is a must for their teachers, as well as for anyone involved in the field of mammalian sex differentiation." Ursula Mittwoch, Nature
"It is a pleasure to read because of Hunter's clear style and elegant exposition....I am pleased to have this concise and well-written summary of what is known and hypothesized about mammalian sex determination on my shelf as a reference. The index is excellent, and there are many important references up to 1994." Barbara R. Migeon, Science
"Based on the depth and sophistication of the subject matter, the book will be useful to graduate students and professionals in reproductive medicine, genetics and molecular and developmental biology." H.S. Pitkow, Choice
"The greatest strength of the book is the uniformity and enthusiasm provided by having a single author who is dedicated to his topic." Aline M. Davis, Trends in Endocrinology and Metabolism
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Product details
- Date Published: April 2011
- format: Paperback
- isbn: 9780521182294
- length: 338 pages
- dimensions: 229 x 152 x 19 mm
- weight: 0.5kg
- availability: Available
Table of Contents
1. Historical landmarks in studies of reproduction and sex determination
2. Mechanisms of sex determination
3. Differentiation of the gonads
4. Differentiation of the genital duct system
5. Anomalous sexual development in domestic species
6. Abnormal sexual development in laboratory rodents
7. Abnormal sexual development in man
8. Sexual differentiation in chimaeras
9. Asymmetries in the reproductive system and their significance
10. Concluding thoughts and a current perspective.
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