Personalized Drug Screening for Functional Tumor Profiling
$22.00 ( ) USD
Part of Elements in Molecular Oncology
- Authors:
- Victoria El-Khoury, Luxembourg Institute of Health
- Tatiana Michel, Luxembourg Institute of Health
- Hichul Kim, Luxembourg Institute of Health
- Yong-Jun Kwon, Luxembourg Institute of Health
- Date Published: June 2022
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
- format: Adobe eBook Reader
- isbn: 9781009037235
Find out more about Cambridge eBooks
$
22.00 USD
( )
Adobe eBook Reader
Other available formats:
Paperback
Looking for an examination copy?
If you are interested in the title for your course we can consider offering an examination copy. To register your interest please contact [email protected] providing details of the course you are teaching.
-
Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology.
Customer reviews
Not yet reviewed
Be the first to review
Review was not posted due to profanity
×Product details
- Date Published: June 2022
- format: Adobe eBook Reader
- isbn: 9781009037235
- availability: This ISBN is for an eBook version which is distributed on our behalf by a third party.
Table of Contents
1. Rationale for functional profiling in oncology
2. Tumor models in drug screening
3. Cell-based screening platforms for personalized medicine
4. Drug repurposing in personalized oncomedicine
5. Clinical applications of drug screening in oncology
6. Conclusions and perspectives
References.
Sorry, this resource is locked
Please register or sign in to request access. If you are having problems accessing these resources please email [email protected]
Register Sign in» Proceed
You are now leaving the Cambridge University Press website. Your eBook purchase and download will be completed by our partner www.ebooks.com. Please see the permission section of the www.ebooks.com catalogue page for details of the print & copy limits on our eBooks.
Continue ×Are you sure you want to delete your account?
This cannot be undone.
Thank you for your feedback which will help us improve our service.
If you requested a response, we will make sure to get back to you shortly.
×