Nitric Oxide in Bone and Joint Disease
$46.99 (M)
Part of Postgraduate Medical Science
- Editors:
- Mika V. J. Hukkanen, University of Helsinki
- Julia M. Polak, Imperial College of Science, Technology and Medicine, London
- Sean P. F. Hughes, Imperial College of Science, Technology and Medicine, London
- Date Published: March 2011
- availability: Available
- format: Paperback
- isbn: 9780521175135
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Nitric oxide research has emerged as one of the most important new areas in bone and joint diseases. This book is the first to bring together current knowledge on the actions of nitric oxide and its role in such common diseases as arthritis and osteoporosis. The volume introduces the basic biology and biochemistry of nitric oxide, the immune response, and bone biology. While doing so, it reviews in depth the facts we know today and the future promise of this exciting area of research. Throughout the book, the authors emphasize potential new treatments that exploit our understanding of the role of nitric oxide in bone and joint disease. This resource will give scientists and clinicians unique insight into this increasingly important area of research.
Read more- Was the first book to review the role of nitric oxide in such common diseases as arthritis and osteoporosis.
- Clinical science from international authorities
- Spans basic and clinical sciences, including therapeutic developments
Reviews & endorsements
"This is a timely and interesting monograph by a group of authors who are experts in their fields...readers will find this monograph a very interesting review of the literature on the areas of nitric oxide in arthritis and nitric oxide in bone." American Journal of Human Biology
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×Product details
- Date Published: March 2011
- format: Paperback
- isbn: 9780521175135
- length: 208 pages
- dimensions: 246 x 189 x 11 mm
- weight: 0.38kg
- availability: Available
Table of Contents
Foreword Julia M. Polak
Part I. Nitric Oxide and Cytokines: An Introduction:
1. A brief overview of the biology of nitric oxide P. Vallance and S. Moncada
2. Nitric oxide and immune responses I. B. McInness and F.Y. Liew
3. Bone biology and pathophysiological mechanisms of bone disease R. G. G. Russell, P. Croucher, B. Oyajobi, S Rahman, M. Rogers and A. Scutt
Part II. Nitric Oxide in Arthritis:
4. Nitric oxide and blood flow in arthritis J. C. Lockhart, L. McMurdo and W. R. Ferrell
5. Effects of nitric oxide synthase inhibitors in experimental models of arthritis C. H. Evans and M. Stefanovic-Racic
6. Nitric oxide and prostaglandin interactions in acute and chronic inflammation D. Salvemini
7. Nitric oxide and cartilage matrix turnover M. Cao, H. J. Hauselmann, M. Stefanovic-Racic and C. H. Evans
8. Nitric oxide production in human inflammatory arthritides N. Miyasaka and Y. Hirata
9. The complex influences of reactive oxygen species on rheumatoid erosions and synovitis J. M. Kanczler, T. Sahinoglu, C. R. Stevens and D. R. Blake
Part III. Nitric Oxide, Bone Cell Function and Osteoporosis:
10. Nitric oxide and osteoblast function F. J. Hughes, L. D. K. Buttery, M. V. J. Hukkanen and J. M. Polak
11. Nitric oxide as a mediator of cytokine effects on bone S. H. Ralston
12. The osteoclast, bone homeostasis and postmenopausal osteoporosis L. Mancini, N. Moradi-Bidhendi and I. MacIntyre
Part IV. Nitric Oxide and Mechanical Factors:
13. Modulation of bone blood flow by nitric oxide I. D. McCarthy
14. Fluid shear stress T. N. McAllister and J. A. Frangos
15. Mechanical strain-associated nitric oxide production by bone cells A. A. Pitsillides and L. E. Lanyon
16. The response of bone and bone cells to mechanical stimulation T. J. Chambers, J. W. M. Chow, S. Fox, R. L. Howard, C. J. Jagger, J. M. Lean, F. T. Mitchell and R. Smalt
17. Aseptic loosening of total hip prostheses S. A. Corbett, M. V. J. Hukkanen, S. P. F. Hughes and J. M. Polak
Index.
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